Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

H3K4me2 accompanies chromatin immaturity in human spermatozoa: an epigenetic marker for sperm quality assessment

3 Oct 2019

Abstract excerpt

Chromatin remodeling, including histone post-translational modifications, during spermatogenesis can affect sperm quality and fertility, and epigenetic marks may therefore be useful for clinical evaluations of sperm. Together with histone hyperacetylation, the dimethylation of histone H3 on lysine K4 (H3K4me2) is also required during protamination. Accordingly, we evaluated the utilization of this epigenetic mark...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31580744
DOI: 10.1080/19396368.2019.1666435

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

H3K4me2 accompanies chromatin immaturity in human spermatozoa: an epigenetic marker for sperm quality assessmentPMID 31580744Read ↗

Sperm chromatin: Evaluation, epigenetic signatures and relevance for embryo development and assisted reproductive technology outcomesSemantic proximity Read ↗

Human Sperm Morphology as a Marker of Its Nuclear Quality and Epigenetic PatternSemantic proximity Read ↗

Essential Role of Histone Replacement and Modifications in Male FertilitySemantic proximity Read ↗

Protamines and DNA integrity as a biomarkers of sperm quality and assisted conception outcomeSemantic proximity Read ↗

Progress in Research on Sperm DNA FragmentationSemantic proximity Read ↗

Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy lossSemantic proximity Read ↗

The human sperm epigenome and its potential role in embryonic developmentSemantic proximity Read ↗

Low human sperm motility coexists with sperm nuclear DNA damage and oxidative stress in semenSemantic proximity Read ↗

Condensation and protamination of sperm chromatin affect ICSI outcomes when gametes from healthy individuals are usedSemantic proximity Read ↗

Differential sperm histone retention in normozoospermic ejaculates of infertile men negatively affects sperm functional competence and embryo qualitySemantic proximity Read ↗

An aberrant protamine ratio is associated with decreased H4ac levels in murine and human spermSemantic proximity Read ↗

Insights into the sperm chromatin and implications for male infertility from a protein perspectiveSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.