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Roundabout signaling pathway involved in the pathogenesis of COPD by integrative bioinformatics analysis

1 Sept 2019

Abstract excerpt

Purpose: To explore the potential mechanism underpinning the development of chronic obstructive pulmonary disease (COPD) and to investigate the role of the Roundabout signaling pathway in COPD. Methods: Three microarray datasets (GSE1650, GSE38974 and GSE76925) including 139 cases of severe COPD and 52 cases of normal smokers without carcinoma, were integrated to screen differentially expressed genes (DEGs) using...

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PMID: 31571851
DOI: 10.2147/copd.s216050

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