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Anoikis resistance of small airway epithelium is involved in the progression of chronic obstructive pulmonary disease

5 Apr 2023

Abstract excerpt

Background Anoikis resistance is recognized as a crucial step in the metastasis of cancer cells. Most epithelial tumors are distinguished by the ability of epithelial cells to abscond anoikis when detached from the extracellular matrix. However, no study has investigated the involvement of anoikis in the small airway epithelium (SAE) of chronic obstructive pulmonary disease (COPD). Methods Anoikis-related genes...

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PMID: 37090717
DOI: 10.3389/fimmu.2023.1155478

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