Article
Proteomic profiling of lung immune cells reveals dysregulation of phagocytotic pathways in female-dominated molecular COPD phenotype.
Respiratory research - 8 Mar 2018
Yang Mingxing, Kohler Maxie, Heyder Tina, Forsslund Helena, Garberg Hilde K, Karimi Reza, Grunewald Johan, Berven Frode S, Nyrén Sven, Magnus Sköld C, Wheelock Åsa M
Abstract excerpt
BACKGROUND: Smoking is the main risk factor for chronic obstructive pulmonary disease (COPD). Women with COPD who smoke experienced a higher risk of hospitalization and worse decline of lung function. Yet the mechanisms of these gender-related differences in clinical presentations in COPD remain unknown. The aim of our study is to identify proteins and molecular pathways associated with COPD pathogenesis, with...
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