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Article

Can mouse models mimic sporadic Alzheimer’s disease?

26 Sept 2019

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia worldwide. As age is the main risk factor, > 97% of all AD cases are of sporadic origin, potentiated by various risk factors associated with life style and starting at an age > 60 years. Only < 3% of AD cases are of genetic origin caused by mutations in the amyloid precursor protein or Presenilins 1 or 2, and...

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PMID: 31571648
DOI: 10.4103/1673-5374.266046

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