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Article

Effect of Environment on the Evolutionary Trajectories and Growth Characteristics of Antibiotic-Resistant Escherichia coli Mutants

28 Aug 2019

Abstract excerpt

The fitness cost to bacteria of acquisition of resistance determinants is critically under-investigated, and the identification and exploitation of these fitness costs may lead to novel therapeutic strategies that prevent the emergence of antimicrobial resistance. Here we used Escherichia coli and amoxicillin-clavulanic acid (AMC) resistance as a model to understand how the artificial environments utilised in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31555237
DOI: 10.3389/fmicb.2019.02001

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