Article
The immune phenotypes and different immune escape mechanisms in colorectal cancer.
Frontiers in immunology - 1 Jan 2022
Mao Yihao, Xu Yuqiu, Chang Jiang, Chang Wenju, Lv Yang, Zheng Peng, Zhang Zhiyuan, Li Zhiqiang, Lin Qi, Tang Wentao, Zhu Dexiang, Ji Meiling, He Guodong, Feng Qingyang, Xu Jianmin
Abstract excerpt
The tumor microenvironment (TME) plays a crucial role in tumor progression and metastasis. However, the immune phenotypes of colorectal cancer (CRC) and the underlying immune escape mechanism have not been studied sufficiently. A total of 1802 and 619 CRC samples from the microarray and TCGA cohorts were enrolled, respectively. The ssGSEA algorithm and unsupervised clustering were used for TME cell infiltration...
Topics
Join the communities discussing this publication.