Article
Chemokines and Their Receptors: Drug Targets in Immunity and Inflammation
20 Sept 2007
Abstract excerpt
The chemokine system coordinates leukocyte migration in immunity and inflammation and is implicated in the pathogenesis of many human diseases. Although several successful strategies have been identified to develop drugs targeting chemokines and their receptors, this has not yet resulted in many new therapeutics. This is likely due to a complexity of the chemokine system, which was not initially appreciated, that...
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