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Article

Assessing causal links between metabolic traits, inflammation and schizophrenia: a univariable and multivariable, bidirectional Mendelian-randomization study

7 Aug 2019

Abstract excerpt

BACKGROUND: Blood immunoreactive biomarkers, such as C-reactive protein (CRP), and metabolic abnormalities have been associated with schizophrenia. Studies comprehensively and bidirectionally probing possible causal links between such blood constituents and liability to schizophrenia are lacking. METHODS: To disentangle putative causal links between CRP blood levels and schizophrenia in both directions, we...

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PMID: 31504541
DOI: 10.1093/ije/dyz176

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