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Article

RhoC regulates radioresistance via crosstalk of ROCK2 with the DNA repair machinery in cervical cancer

5 Sept 2019

Abstract excerpt

BACKGROUND: Radioresistance remains a challenge to the successful treatment of various tumors. Intrinsic factors like alterations in signaling pathways regulate response to radiation. RhoC, which has been shown to modulate several tumor phenotypes has been investigated in this report for its role in radioresistance. In vitro and clinical sample-based studies have been performed to understand its contribution to...

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PMID: 31488179
DOI: 10.1186/s13046-019-1385-7

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