Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RhoC: a fascinating journey from a cytoskeletal organizer to a Cancer stem cell therapeutic target

24 Jul 2019

Abstract excerpt

Tumor heterogeneity results in differential response to therapy due to the existence of plastic tumor cells, called cancer stem cells (CSCs), which exhibit the property of resistance to therapy, invasion and metastasis. These cells have a distinct, signaling network active at every stage of progression. It is difficult to envisage that the CSCs will have a unique set of signaling pathways regulating every stage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to FOXO transcription factor regulation
Share to Hippo pathway signaling and YAP/TAZ

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31340863
DOI: 10.1186/s13046-019-1327-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RhoC: a fascinating journey from a cytoskeletal organizer to a Cancer stem cell therapeutic targetPMID 31340863Read ↗

RhoC Impacts the Metastatic Potential and Abundance of Breast Cancer Stem CellsSemantic proximity Read ↗

RASSF1C oncogene elicits amoeboid invasion, cancer stemness and invasive EVs via a novel SRC/Rho axisSemantic proximity Read ↗

Role of Rho GTPases in stem cell regulationSemantic proximity Read ↗

Rho proteins and cancer.Semantic proximity Read ↗

Targeting Rho GTPase Signaling Networks in CancerSemantic proximity Read ↗

Rho Kinases in Embryonic Development and Stem Cell ResearchSemantic proximity Read ↗

Comprehensive analysis on the whole Rho‐GAP family reveals that ARHGAP4 suppresses EMT in epithelial cells under negative regulation by Septin9Semantic proximity Read ↗

Cytoskeletal and Cytoskeleton-Associated Proteins: Key Regulators of Cancer Stem Cell PropertiesSemantic proximity Read ↗

Fixing the GAP: The role of RhoGAPs in cancerSemantic proximity Read ↗

RhoC Regulates Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma by Overexpressing IL-6 and Phosphorylation of STAT3Semantic proximity Read ↗

p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells.Semantic proximity Read ↗

RHOA takes the RHOad less traveled to cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.