Article
A clinical prediction model for beta cell monogenetic diabetes in Chinese patients with early-onset type 2 diabetes.
Diabetes & metabolism - 1 Mar 2026
Sun Siyu, Gong Siqian, Ba Tianhao, Li Meng, Liu Wei, Zhang Rui, Ma Yumin, Wang Fang, Cai Xiaoling, Luo Yingying, Zhang Simin, Zhou Lingli, Zhu Yu, Zhang Xiuying, Chen Jing, Chen Ling, Wu Jing, Gao Leili, Zhou Xianghai, Zhong Liyong, Wang Xirui, Xiao Xinhua, Gu Weijun, Yang Jinkui, Wang Qiuping, Deng Wei, Qi Lin, Wang Wenbo, Lian Hong, Li Yufeng, Ren Qian, Han Xueyao, Ji Linong
Abstract excerpt
AIM: Monogenic diabetes is a group of disorders arising from single gene mutations with a clear pathophysiology, most of which present with impaired beta cell function rather than insulin resistance. This study aims to evaluate the ability of TyG index and polygenetic risk score (PRS) to identify multi-type beta cell monogenetic diabetes (beta-cell-MgD) in Chinese early-onset type 2 diabetes (EOD) population....
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