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Article

PLOD2 contributes to drug resistance in laryngeal cancer by promoting cancer stem cell-like characteristics

27 Aug 2019

Abstract excerpt

BACKGROUND: Advanced stage laryngeal squamous cell carcinoma (LSCC) presents a poor prognosis; thus, there is a great need to identify novel prognostic molecular markers. Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) is thought to be a novel prognostic factor in several cancers, but its role in LSCC remains unknown. Cancer stem cells (CSCs) are responsible for most instances of tumor recurrence and...

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PMID: 31455288
DOI: 10.1186/s12885-019-6029-y

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