Article

The PLOD2 promotes tumor progression in colorectal cancer through the PI3K-AKT pathway

2024-10-23

Abstract excerpt

<title>Abstract</title> <p>Based on reports, Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) constitutes an oncogenic gene that undergoes upregulation in multiple malignancies, encompassing cervical cancer, endometrial cancer, and lung cancer. PLOD2 is competent to stiffen the extracellular matrix and modify the ECM architecture. Despite the fact that PLOD2 has been demonstrated to be associated with a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 854fb8a5-eeb5-59b0-98d3-601a5f6eb5fd
DOI: 10.21203/rs.3.rs-5266104/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The PLOD2 promotes tumor progression in colorectal cancer through the PI3K-AKT pathwayDOI 10.21203/rs.3.rs-5266104/v1Read

Integrated Profiling Identifies PLOD3 as a Potential Prognostic and Immunotherapy Relevant Biomarker in Colorectal Cancer.Semantic proximity Read

A Human Pan-Cancer System Analysis of Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3).Semantic proximity Read

Characterization of Procollagen-lysine, 2-oxoglutarate 5-dioxygenases as Therapeutic Targets in a Pan-Cancer StudySemantic proximity Read

PLOD3 is Upregulated in Gastric Cancer and Correlated with Clinicopathologic CharacteristicsSemantic proximity Read

PLOD2 as a potential regulator of peritoneal dissemination in gastric cancerSemantic proximity Read

Overexpressing PLOD Family Genes Predict Poor Prognosis In Pancreatic CancerSemantic proximity Read

Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in gliomaSemantic proximity Read

SH2D2A as a VEGF pathway-related oncogene driving colorectal cancer through mTOR activationSemantic proximity Read

Comprehensive Analysis of the Expression, Prognosis, and Biological Significance of PLOD Family in Bladder CancerSemantic proximity Read

Hypomethylation induced overexpression of PLOD3 facilitates colorectal cancer progression through TM9SF4-mediated autophagySemantic proximity Read

PTGDS is a potential marker for lung adenocarcinoma identified from multi-omics pan-cancer dataSemantic proximity Read

Comprehensive Analysis of PLOD Family Members in Low-grade Gliomas Using Bioinformatics MethodsSemantic proximity Read