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Article

Identification of Unique microRNA Profiles in Different Types of Idiopathic Inflammatory Myopathy

2 Sept 2023

Abstract excerpt

Dermatomyositis (DM), antisynthetase syndrome (AS), immune-mediated necrotizing myopathy (IMNM), and inclusion body myositis (IBM) are four major types of idiopathic inflammatory myopathy (IIM). Muscle biopsies from each type of IIM have unique transcriptomic profiles. MicroRNAs (miRNAs) target messenger RNAs (mRNAs), thereby regulating their expression and modulating transcriptomic profiles. In this study, 18...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37681930
DOI: 10.3390/cells12172198

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