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Article

The Emerging Role of H3K9me3 as a Potential Therapeutic Target in Acute Myeloid Leukemia

2 Aug 2019

Abstract excerpt

Growing evidence has demonstrated that epigenetic dysregulation is a common pathological feature in human cancer cells. Global alterations in the epigenetic landscape are prevalent in malignant cells across different solid tumors including, prostate cancer, non-small-cell lung cancer, renal cell carcinoma, and in haemopoietic malignancy. In particular, DNA hypomethylation and histone hypoacetylation have been...

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PMID: 31428579
DOI: 10.3389/fonc.2019.00705

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