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Article

Immune Cytolytic Activity Is Associated With Genetic and Clinical Properties of Glioma

2 Aug 2019

Abstract excerpt

Background: Immunotherapy provided unprecedented advances in the treatment of several previously untreated cancers. However, these immunomodulatory maneuvers showed limited response to patients with glioma in clinical trials. Our aim was to depict the immune characteristics of glioma with immune cytolytic activity at genetic and transcriptome levels. Methods: In total, 325 gliomas from CGGA dataset as training...

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PMID: 31428092
DOI: 10.3389/fimmu.2019.01756

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