Article
Dissecting Tumor Antigens and Immune Subtypes of Glioma to Develop mRNA Vaccine.
Frontiers in immunology - 1 Jan 2021
Zhong Hua, Liu Shuai, Cao Fang, Zhao Yi, Zhou Jianguo, Tang Feng, Peng Zhaohua, Li Yangsheng, Xu Shen, Wang Chunlin, Yang Guohua, Li Zhi-Qiang
Abstract excerpt
Background: Nowadays, researchers are leveraging the mRNA-based vaccine technology used to develop personalized immunotherapy for cancer. However, its application against glioma is still in its infancy. In this study, the applicable candidates were excavated for mRNA vaccine treatment in the perspective of immune regulation, and suitable glioma recipients with corresponding immune subtypes were further...
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