Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trypanosoma brucei Homologue of Regulator of Ribosome Synthesis 1 (Rrs1) Has Direct Interactions with Essential Trypanosome-Specific Proteins

6 Aug 2019

Abstract excerpt

Trypanosoma brucei is a parasite responsible for human and animal African trypanosomiasis. Current treatments for these diseases have numerous problems, and the development of novel chemotherapeutics can be achieved by identifying targets that are parasite specific and part of essential processes. Ribosome biogenesis is the process of generating translation-competent ribosomes and is critical for survival in all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biochemical and Molecular Research
Share to RNA modifications and cancer
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31391282
DOI: 10.1128/msphere.00453-19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trypanosoma brucei Homologue of Regulator of Ribosome Synthesis 1 (Rrs1) Has Direct Interactions with Essential Trypanosome-Specific ProteinsPMID 31391282Read ↗

Trypanosoma brucei L11 Is Essential to Ribosome Biogenesis and Interacts with the Kinetoplastid-Specific Proteins P34 and P37Semantic proximity Read ↗

Non-canonical binding interactions of the RNA recognition motif (RRM) domains of P34 protein modulate binding within the 5S ribonucleoprotein particle (5S RNP).Semantic proximity Read ↗

Characterization of a novel association between two trypanosome-specific proteins and 5S rRNA.Semantic proximity Read ↗

Pentatricopeptide Repeat Proteins in Trypanosoma brucei Function in Mitochondrial RibosomesSemantic proximity Read ↗

Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian HostsSemantic proximity Read ↗

Structural differences in translation initiation between pathogenic trypanosomatids and their mammalian hostsSemantic proximity Read ↗

Extensive Translational Regulation through the Proliferative Transition of Trypanosoma cruzi Revealed by Multi-OmicsSemantic proximity Read ↗

The Influence of Extra-Ribosomal Functions of Eukaryotic Ribosomal Proteins on Viral InfectionSemantic proximity Read ↗

Key RNA-binding domains in the La protein establish tRNA modification levels in Trypanosoma bruceiSemantic proximity Read ↗

Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomesSemantic proximity Read ↗

Novel aspects of iron homeostasis in pathogenic bloodstream form <i>Trypanosoma brucei</i>Semantic proximity Read ↗

Novel aspects of iron homeostasis in pathogenic bloodstream form Trypanosoma bruceiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.