Article
Characterization of a novel association between two trypanosome-specific proteins and 5S rRNA.
PloS one - 1 Jan 2012
Ciganda Martin, Williams Noreen
Abstract excerpt
P34 and P37 are two previously identified RNA binding proteins in the flagellate protozoan Trypanosoma brucei. RNA interference studies have determined that the proteins are essential and are involved in ribosome biogenesis. Here, we show that these proteins interact in vitro with the 5S rRNA with nearly identical binding characteristics in the absence of other cellular factors. The T. brucei 5S rRNA has a...
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