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Article

A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3

27 Jul 2019

Abstract excerpt

The roles of SUMOylation and the related enzymes in autophagic regulation are unclear. Based on our previous studies that identified the SUMO2/3-specific peptidase SENP3 as an oxidative stress-responsive molecule, we investigated the correlation between SUMOylation and macroautophagy/autophagy. We found that Senp3± mice showed increased autophagy in the liver under basal and fasting conditions, compared to...

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Identifiers

PMID: 31373534
DOI: 10.1080/15548627.2019.1647944

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