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Microbial dysbiosis and polyamine metabolism as predictive markers for early detection of pancreatic cancer.

Carcinogenesis - 10 Jul 2020

Mendez Roberto, Kesh Kousik, Arora Nivedita, Di Martino Leá, McAllister Florencia, Merchant Nipun, Banerjee Sulagna, Banerjee Santanu

Abstract excerpt

The lack of tools for early detection of pancreatic ductal adenocarcinoma (PDAC) is directly correlated with the abysmal survival rates in patients. In addition to several potential detection tools under active investigation, we tested the gut microbiome and its metabolic complement as one of the earliest detection tools that could be useful in patients at high risk for PDAC. We used a combination of 16s rRNA...

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Identifiers

PMID: 31369062
DOI: 10.1093/carcin/bgz116
PMCID: PMC7350554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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