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Integrated analysis of microbiome and metabolome reveals signatures in PDAC tumorigenesis and prognosis

10 Oct 2024

Abstract excerpt

ABSTRACT Pancreatic cancer, predominantly pancreatic ductal adenocarcinoma (PDAC), is one of the most malignant tumors of the digestive system. Emerging evidence suggests the involvement of the microbiome and metabolic substances in the development of PDAC, yet the results remain contradictory. This study aims to identify the alterations and relationships in intratumoral microbiome and metabolites in PDAC. We...

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PMID: 39387592
DOI: 10.1128/spectrum.00962-24

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