Article
Role of epigenetic modifications in the aberrant CYP19A1 gene expression in polycystic ovary syndrome
1 Jan 2019
Abstract excerpt
Introduction: In this study, the global DNA methylation, histone acetylation and methylation levels of cumulus cells (CCs) in infertile polycystic ovary syndrome (PCOS) patients and the correlation of these epigenetic modifications with the expression of the ovarian aromatase gene (as an important marker in the etiology of PCOS) were investigated. Material and methods: A cross-sectional study was conducted on 24...
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