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Article

DNA methylation in the pathogenesis of polycystic ovary syndrome

8 Apr 2019

Abstract excerpt

Polycystic ovary syndrome (PCOS) is the leading endocrine and metabolic disorder in premenopausal women characterized by hyperandrogenism and abnormal development of ovarian follicles. To date, the PCOS etiology remains unclear and has been related to insulin resistance, obesity, type 2 diabetes mellitus, cardiovascular disease and infertility, among other morbidities. Substantial evidence illustrates the impact...

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PMID: 30959484
DOI: 10.1530/rep-18-0449

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