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Article

Epigenetic regulation in premature ovarian failure: A literature review

4 Jan 2023

Abstract excerpt

Premature ovarian failure (POF), or premature ovarian insufficiency (POI), is a multifactorial and heterogeneous disease characterized by amenorrhea, decreased estrogen levels and increased female gonadotropin levels. The incidence of POF is increasing annually, and POF has become one of the main causes of infertility in women of childbearing age. The etiology and pathogenesis of POF are complex and have not yet...

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PMID: 36685174
DOI: 10.3389/fphys.2022.998424

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