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Article

White Matter in Schizophrenia Treatment Resistance

29 Jul 2019

Abstract excerpt

OBJECTIVE: Failure of antipsychotic medications to resolve symptoms in patients with schizophrenia creates a clinical challenge that is known as treatment resistance. The causes of treatment resistance are unknown, but it is associated with earlier age at onset and more severe cognitive deficits. The authors tested the hypothesis that white matter deficits that are involved in both neurodevelopment and severity...

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PMID: 31352812
DOI: 10.1176/appi.ajp.2019.18101212

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