Article
Heterogeneity of response to antipsychotics from multiple disorders in the schizophrenia spectrum.
The Journal of clinical psychiatry - 1 Dec 2000
Garver D L, Holcomb J A, Christensen J D
Abstract excerpt
BACKGROUND: Antipsychotic response after the initiation of neuroleptic treatment shows wide variation in schizophrenic patient populations. In this overview, the authors suggest that the variance in antipsychotic drug response within schizophrenia can be reduced by resolving the schizophrenias into several discrete "endophenotypes," each with different etiologic underpinnings. METHOD: Studies relating differences...
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