Article

Assessing regional intracortical myelination in schizophrenia spectrum and bipolar disorders using the optimized T1w/T2w-ratio

2023-06-05

Abstract excerpt

<h4>Background</h4> Dysmyelination could be part of the pathophysiology of schizophrenia spectrum (SCZ) and bipolar disorders (BPD), yet few studies have examined myelination of the cerebral cortex. The ratio of T1- and T2-weighted magnetic resonance images (MRI) correlates with intracortical myelin. We investigated the T1w/T2w-ratio and its age trajectories in patients and healthy controls (CTR) and explored asso...

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Literature Corpus work: 4dea89c3-c763-5150-a600-6a83a11e1412
DOI: 10.1101/2023.06.02.23290882

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