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Diagnostic and prognostic contribution of targeted NGS in patients with triple‐negative myeloproliferative neoplasms

19 Jul 2019

Abstract excerpt

Philadelphia negative myeloproliferative neoplasms (MPN Ph-) are clonal hematopoietic stem cell disorders characterized by proliferation in one or more myeloid cell lineages. Somatic mutations in JAK2, CALR and MPL genes currently constitute major diagnostic criteria according to the 2017 revised World Health Organization Classification.1 However, a subset (10-15%) of MPN Ph- patients, the so-called...

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PMID: 31321810
DOI: 10.1002/ajh.25580

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