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Article

Multinomial modelling of TB/HIV co-infection yields a robust predictive signature and generates hypotheses about the HIV+TB+ disease state

15 Jul 2019

Abstract excerpt

BACKGROUND: Current diagnostics are inadequate to meet the challenges presented by co-infection with Mycobacterium tuberculosis (Mtb) and HIV, the leading cause of death for HIV-infected individuals. Improved characterization of Mtb/HIV coinfection as a distinct disease state may lead to better identification and treatment of affected individuals. METHODS: Four previously-published TB and HIV co-infection related...

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PMID: 31306460
DOI: 10.1371/journal.pone.0219322

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