Article
Applications of emerging molecular technologies in glioblastoma multiforme.
Expert review of neurotherapeutics - 1 Oct 2008
Kumar Hari R, Zhong Xiaoling, Sandoval John A, Hickey Robert J, Malkas Linda H
Abstract excerpt
Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. Median survival from the time of diagnosis is less than a year, with less than 5% of patients surviving 5 years. These tumors are thought to arise through two different pathways. Primary GBMs represent de novo tumors, while secondary GBMs represent the malignant progression of lower-grade astrocytomas. Moreover, despite improvements...
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