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Article

Chemokine Receptor Crystal Structures: What Can Be Learned from Them?

3 Jul 2019

Abstract excerpt

Chemokine receptors belong to the class A of G protein-coupled receptors (GPCRs) and are implicated in a wide variety of physiologic functions, mostly related to the homeostasis of the immune system. Chemokine receptors are also involved in multiple pathologic processes, including immune and autoimmune diseases, as well as cancer. Hence, several members of this GPCR subfamily are considered to be very relevant...

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PMID: 31266800
DOI: 10.1124/mol.119.117168

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