Chemokine receptor antagonists: Part 1

Abstract excerpt

BACKGROUND: Chemokines were originally defined as host defense proteins, however, their biological role goes well beyond this simple description of their function as immune cell chemoattractants, and they have since been shown to be involved in a number of other biological processes, including growth regulation, hematopoiesis, embryologic development, angiogenesis, and HIV-1 infection. Because of their diverse...

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