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Sex specific associations in genome wide association analysis of renal cell carcinoma

23 Jun 2019

Abstract excerpt

Renal cell carcinoma (RCC) has an undisputed genetic component and a stable 2:1 male to female sex ratio in its incidence across populations, suggesting possible sexual dimorphism in its genetic susceptibility. We conducted the first sex-specific genome-wide association analysis of RCC for men (3227 cases, 4916 controls) and women (1992 cases, 3095 controls) of European ancestry from two RCC genome-wide scans and...

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Share to Epigenetics and DNA Methylation
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PMID: 31231134
DOI: 10.1038/s41431-019-0455-9

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