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Article

Alterations of Calcium Channels in a Mouse Model of Huntington’s Disease and Neuroprotection by Blockage of Ca V 1 Channels

1 Jan 2019

Abstract excerpt

Huntington’s disease (HD) is a neurodegenerative autosomal dominant disorder, characterized by symptoms of involuntary movement of the body, loss of cognitive function, psychiatric disorder, leading inevitably to death. It has been previously described that higher levels of brain expression of Cav1 channels are involved in major neurodegenerative disorders, such as Alzheimer’s disease and Parkinson’s disease. Our...

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PMID: 31216184
DOI: 10.1177/1759091419856811

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