Article
Inherited Mutations in Chinese Men With Prostate Cancer.
Journal of the National Comprehensive Cancer Network : JNCCN - 15 Oct 2021
Zhu Yao, Wei Yu, Zeng Hao, Li Yonghong, Ng Chi-Fai, Zhou Fangjian, He Caiyun, Sun Guangxi, Ni Yuchao, Chiu Peter K F, Teoh Jeremy Y C, Wang Beihe, Pan Jian, Wan Fangning, Dai Bo, Qin Xiaojian, Lin Guowen, Gan Hualei, Wu Junlong, Ye Dingwei
Abstract excerpt
BACKGROUND: Although China accounts for 7.8% of worldwide new prostate cancer (PCa) cases and 14.5% of new deaths according to GLOBOCAN 2020, the risk of PCa associated with germline mutations is poorly defined, hampered in part by lack of nationwide evidence. Here, we sequenced 19 PCa predisposition genes in 1,836 Chinese patients with PCa and estimated disease risk associated with inherited mutations. PATIENTS...
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