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Flagellin hypervariable region determines symbiotic properties of commensal Escherichia coli strains

17 Jun 2019

Abstract excerpt

Escherichia coli represents a classical intestinal gram-negative commensal. Despite this commensalism, different E. coli strains can mediate disparate immunogenic properties in a given host. Symbiotic E. coli strains such as E. coli Nissle 1917 (EcN) are attributed beneficial properties, e.g., promotion of intestinal homeostasis. Therefore, we aimed to identify molecular features derived from symbiotic bacteria...

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PMID: 31206517
DOI: 10.1371/journal.pbio.3000334

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