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Immune-related somatic mutation genes are enriched in PDACs with diabetes

12 Jun 2019

Abstract excerpt

The bidirectional interaction between pancreatic cancer (PanCa) and diabetes has been confirmed by epidemiological studies, but until now, the underlying molecular mechanisms for this connection is not fully understood yet. Here, we analyzed the clinical and genomic data of 26 pancreatic ductal adenocarcinoma (PDAC) patients without diabetes, and six diabetic PDAC patients, whose tumors underwent targeted...

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PMID: 31203147
DOI: 10.1016/j.tranon.2019.03.006

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