Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allele Loss and Reduced Expression of CYCLOPS Genes is a Characteristic Feature of Chromophobe Renal Cell Carcinoma

11 Jun 2019

Abstract excerpt

Copy-number alterations Yielding Cancer Liabilities Owing to Partial losS (CYCLOPS) genes have been recently identified as the most enriched class of copy-number associated gene dependencies in human cancer. These genes are cell essential and render tumor cells highly sensitive to the expression of the remaining copy. Chromophobe renal cell carcinoma (chRCC) is characterized by frequent chromosomal deletions, but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Renal and related cancers
Share to Renal cell carcinoma treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31200327
DOI: 10.1016/j.tranon.2019.05.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allele Loss and Reduced Expression of CYCLOPS Genes is a Characteristic Feature of Chromophobe Renal Cell CarcinomaPMID 31200327Read ↗

Loss of CDKN1A mRNA and Protein Expression Are Independent Predictors of Poor Outcome in Chromophobe Renal Cell Carcinoma PatientsSemantic proximity Read ↗

Genomic landscape and evolution of metastatic chromophobe renal cell carcinomaSemantic proximity Read ↗

Genetic Profiling Uncovers Genome-Wide Loss of Heterozygosity and Provides Insight into Mechanisms of Sarcomatoid Transformation in Chromophobe Renal Cell CarcinomaSemantic proximity Read ↗

Comprehensive Review of Numerical Chromosomal Aberrations in Chromophobe Renal Cell Carcinoma Including Its Variant MorphologiesSemantic proximity Read ↗

Interrogation of cancer gene dependencies reveals novel paralog interactions of autosome and sex chromosome encoded genesSemantic proximity Read ↗

Somatic Copy Number Alterations and Associated Genes in Clear-Cell Renal-Cell Carcinoma in Brazilian PatientsSemantic proximity Read ↗

The Somatic Genomic Landscape of Chromophobe Renal Cell CarcinomaSemantic proximity Read ↗

Molecular underpinnings of dedifferentiation and aggressiveness in chromophobe renal cell carcinoma.Semantic proximity Read ↗

Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma.Semantic proximity Read ↗

Genomic Copy Number Alterations in Renal Cell Carcinoma with Sarcomatoid Features.Semantic proximity Read ↗

Abundant copy-number loss of CYCLOPS and STOP genes in gastric adenocarcinoma.Semantic proximity Read ↗

Integrative Analysis of 1q23.3 Copy-Number Gain in Metastatic Urothelial CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.