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Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages

12 Jun 2019

Abstract excerpt

RATIONALE: The developing heart is composed of cardiomyocytes and noncardiomyocytes since the early stage. It is generally believed that noncardiomyocytes including the cardiac progenitors contribute to new cardiomyocytes of the looping heart. However, it remains unclear what the cellular dynamics of nonmyocyte to cardiomyocyte conversion are and when the lineage segregation occurs during development. It also...

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PMID: 31185811
DOI: 10.1161/circresaha.119.315280

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