Article
Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases.
Circulation - 21 Aug 2018
Li Yan, He Lingjuan, Huang Xiuzhen, Bhaloo Shirin Issa, Zhao Huan, Zhang Shaohua, Pu Wenjuan, Tian Xueying, Li Yi, Liu Qiaozhen, Yu Wei, Zhang Libo, Liu Xiuxiu, Liu Kuo, Tang Juan, Zhang Hui, Cai Dongqing, Ralf Adams H, Xu Qingbo, Lui Kathy O, Zhou Bin
Abstract excerpt
BACKGROUND: Whether the adult mammalian heart harbors cardiac stem cells for regeneration of cardiomyocytes is an important yet contentious topic in the field of cardiovascular regeneration. The putative myocyte stem cell populations recognized without specific cell markers, such as the cardiosphere-derived cells, or with markers such as Sca1+, Bmi1+, Isl1+, or Abcg2+ cardiac stem cells have been reported....
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