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Cre-loxP-mediated genetic lineage tracing: Unraveling cell fate and origin in the developing heart

27 Feb 2023

Abstract excerpt

The Cre-loxP-mediated genetic lineage tracing system is essential for constructing the fate mapping of single-cell progeny or cell populations. Understanding the structural hierarchy of cardiac progenitor cells facilitates unraveling cell fate and origin issues in cardiac development. Several prospective Cre-loxP-based lineage-tracing systems have been used to analyze precisely the fate determination and...

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PMID: 36923960
DOI: 10.3389/fcvm.2023.1085629

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