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Article

Ally to adversary: mesenchymal stem cells and their transformation in leukaemia

21 May 2019

Abstract excerpt

Mesenchymal stem cells (MSC) are the key regulators of hematopoiesis. Owing to their dynamic nature; MSC differentiate into various lineages that further constitute the niche which are required for maintenance of the hematopoietic stem cells (HSC). A plethora of growth factors and cytokines secreted by MSC are essential for regulating the homeostasis within the niche in terms of cycling and quiescence of HSC....

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PMID: 31139016
DOI: 10.1186/s12935-019-0855-5

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