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ATL-derived exosomes modulate mesenchymal stem cells: potential role in leukemia progression

19 Oct 2016

Abstract excerpt

BACKGROUND: Exosomes are membrane nano-vesicles secreted by a multitude of cells that harbor biological constituents such as proteins, lipids, mRNA and microRNA. Exosomes can potentially transfer their cargo to other cells, implicating them in many patho-physiological processes. Mesenchymal stem cells (MSCs), residents of the bone marrow and metastatic niches, potentially interact with cancer cells and/or their...

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PMID: 27760548
DOI: 10.1186/s12977-016-0307-4

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