Article
Mesenchymal stem cells promote leukaemic cells aberrant phenotype from B-cell acute lymphoblastic leukaemia.
Hematology/oncology and stem cell therapy - 1 Jan 2000
Rodríguez-Pardo Viviana M, Aristizabal José A, Jaimes Diana, Quijano Sandra M, de los Reyes Iliana, Herrera María Victoria, Solano Julio, Vernot Jean Paul
Abstract excerpt
BACKGROUND AND OBJECTIVES: The role of bone marrow-mesenchymal stem cells (BM-MSC) in leukaemic cell control is controversial. The purpose of this work was to evaluate BM-MSC role regarding the viability, proliferation and immunophenotype of normal B-cell precursors from control (Ct) patients and leukaemic cells from B-acute lymphoblastic leukaemia (B-ALL) patients. PATIENTS AND METHODS: BM-MSC were isolated and...
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