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Mesenchymal stromal cell-associated migrasomes: a new source of chemoattractant for cells of hematopoietic origin

14 Feb 2023

Abstract excerpt

Abstract Background Multipotent mesenchymal stromal cells (MSCs) are precursors of various cell types. Through soluble factors, direct cell–cell interactions and other intercellular communication mechanisms such as extracellular vesicles and tunneling nanotubes, MSCs support tissue homeostasis. In the bone marrow microenvironment, they promote hematopoiesis. The interaction between MSCs and cancer cells enhances...

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PMID: 36788616
DOI: 10.1186/s12964-022-01028-6

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