Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatocyte-like cells derived from human induced pluripotent stem cells using small molecules: implications of a transcriptomic study

11 Sept 2020

Abstract excerpt

BACKGROUND: Hepatocyte-like cells (HLCs) derived from human induced pluripotent stem cells (iPSCs) hold great promise in toxicological applications as well as in regenerative medicine. Previous efforts on hepatocyte differentiation have mostly relied on the use of growth factors (GFs) to recapitulate developmental signals under in vitro conditions. Recently, the use of small molecules (SMs) has emerged as an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver physiology and pathology
Share to Pancreatic function and diabetes
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32917265
DOI: 10.1186/s13287-020-01914-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatocyte-like cells derived from human induced pluripotent stem cells using small molecules: implications of a transcriptomic studyPMID 32917265Read ↗

Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes.Semantic proximity Read ↗

Pluripotent Stem Cell-Derived Hepatocyte-like Cells: Induction Methods and ApplicationsSemantic proximity Read ↗

Differentiation of Hepatocytes from Pluripotent Stem CellsSemantic proximity Read ↗

Pluripotent Stem Cell–Derived Hepatocytes: Potential and Challenges in PharmacologySemantic proximity Read ↗

Hepatocyte-like cells differentiated from human induced pluripotent stem cells: Relevance to cellular therapiesSemantic proximity Read ↗

Current Status and Challenges of Human Induced Pluripotent Stem Cell-Derived Liver Models in Drug DiscoverySemantic proximity Read ↗

Human Induced Pluripotent Stem Cells in HepatologySemantic proximity Read ↗

Thyroid hormone and ALK5 inhibitor improve maturation of human pluripotent stem cell derived hepatocytesSemantic proximity Read ↗

Guide to the Assessment of Mature Liver Gene Expression in Stem Cell-Derived HepatocytesSemantic proximity Read ↗

Hepatic differentiation of human pluripotent stem cells in miniaturized format suitable for high-throughput screenSemantic proximity Read ↗

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapySemantic proximity Read ↗

A comprehensive transcriptomic comparison of hepatocyte model systems improves selection of models for experimental useSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.