Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of Cholesterol Homeostasis by a Novel Long Non-coding RNA LASER

22 May 2019

Abstract excerpt

Genome-wide association studies (GWAS) have identified many genetic variants in genes related to lipid metabolism. However, how these variations affect lipid levels remains elusive. Long non-coding RNAs (lncRNAs) have been implicated in a variety of biological processes. We hypothesize lncRNAs are likely to be located within disease or trait-associated DNA regions to regulate lipid metabolism. The aim of this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Lipid metabolism and disorders
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31118464
DOI: 10.1038/s41598-019-44195-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of Cholesterol Homeostasis by a Novel Long Non-coding RNA LASERPMID 31118464Read ↗

The Long Non-coding Road to Atherosclerosis.Semantic proximity Read ↗

Potential therapeutic targeting of lncRNAs in cholesterol homeostasisSemantic proximity Read ↗

Progress and prospects of long noncoding RNAs in lipid homeostasisSemantic proximity Read ↗

Precision Regulation of LDL Metabolism: Epigenetic and Genetic Approaches Targeting LDLR, APOB, and PCSK9Semantic proximity Read ↗

Cold shock domain–containing protein E1 is a posttranscriptional regulator of the LDL receptorSemantic proximity Read ↗

CSDE1 is a Post-Transcriptional Regulator of the LDL ReceptorSemantic proximity Read ↗

A bidirectional interaction between the SREBP pathway and the LINC complex component nesprin-4 controls lipid metabolismSemantic proximity Read ↗

RP1-13D10.2 Is a Novel Modulator of Statin-Induced Changes in Cholesterol.Semantic proximity Read ↗

Long noncoding RNA LINC00305 promotes inflammation by activating the AHRR-NF-κB pathway in human monocytes.Semantic proximity Read ↗

A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levelsSemantic proximity Read ↗

Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine.Semantic proximity Read ↗

Retinoic acid receptor-related orphan receptor α reduces lipid droplets by upregulating neutral cholesterol ester hydrolase 1 in macrophagesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.