Article
Long noncoding RNA LINC00305 promotes inflammation by activating the AHRR-NF-κB pathway in human monocytes.
Scientific reports - 10 Apr 2017
Zhang Dan-Dan, Wang Wen-Tian, Xiong Jian, Xie Xue-Min, Cui Shen-Shen, Zhao Zhi-Guo, Li Mulin Jun, Zhang Zhu-Qin, Hao De-Long, Zhao Xiang, Li Yong-Jun, Wang Junwen, Chen Hou-Zao, Lv Xiang, Liu De-Pei
Abstract excerpt
Accumulating data from genome-wide association studies (GWAS) have provided a collection of novel candidate genes associated with complex diseases, such as atherosclerosis. We identified an atherosclerosis-associated single-nucleotide polymorphism (SNP) located in the intron of the long noncoding RNA (lncRNA) LINC00305 by searching the GWAS database. Although the function of LINC00305 is unknown, we found that...
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